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PubMed COVID-19 Clinical Care

40151 - 40160 of 44979 results found

Abdominal Organ Transplantation: Noteworthy Literature in 2022

Date
Monday, April 10, 2023 - 4:00 AM
Description
This review highlights noteworthy literature published in 2022 pertinent to anesthesiologists and critical care physicians caring for patients undergoing abdominal organ transplantation. We begin by exploring the impacts that the COVID-19 pandemic

Green and efficient one-pot three-component synthesis of novel drug-like furo[2,3-d]pyrimidines as potential active site inhibitors and putative allosteric hotspots modulators of both SARS-CoV-2 MPro and PLPro

Date
Monday, April 10, 2023 - 4:00 AM
Description
In this paper, an environmentally benign, convenient, and efficient one-pot three-component reaction has been developed for the regioselective synthesis of novel 5-aroyl(or heteroaroyl)-6-(alkylamino)-1,3-dimethylfuro[2,3-d]pyrimidine-2,4(1H,3H)

Exploring polyamine interactions and binding pockets in SARS-CoV-2 ORF3a

Date
Monday, April 10, 2023 - 4:00 AM
Description
Ongoing global pandemic caused by coronavirus (COVID-19) requires urgent development of vaccines, treatments, and diagnostic tools. Open reading frame 3a (ORF3a) from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered to be a